Self-neutralizing acid peel for dermatologic use

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/02 (2006.01) A61K 8/26 (2006.01) A61K 8/36 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2656055

A dermatologic peel comprising alpha hydroxyl acid and metal hydroxide nanocomplexes as neutralizing agents to continually reduce the activity of the system when the acid and neutralizer components are mixed. For example, a 30% glycolic acid gel mixed with a fluidized magaldrate neutralizer can be applied to the skin and will self-neutralize to a skin-compatible pH within a few minutes, effectively exfoliating the skin without a separate neutralization step. The peel is advantageously applied from a two-component system that mixes the components.

L'invention concerne un peeling dermatologique comprenant des nanocomplexes d'hydroxyde métallique et d'acide alpha hydroxyle en tant qu'agents neutralisants afin de réduire continuellement l'activité du système lorsque les composants acide et neutralisant sont mélangés. Par exemple, un gel à 30 % d'acide glycolique mélangé avec un neutralisant de magaldrate fluidisé peut être appliqué sur la peau et s'auto-neutralisera à un pH compatible avec la peau en quelques minutes, exfoliant ainsi la peau de manière efficace sans étape distincte de neutralisation. De manière avantageuse, le peeling est appliqué à partir d'un système bicomposant qui mélange les composants.

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