Self-supporting, shaped, three-dimensional biopolymeric...

A - Human Necessities – 61 – L

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Details

A61L 31/14 (2006.01) A61F 2/20 (2006.01) A61L 24/00 (2006.01) A61L 27/22 (2006.01) A61L 27/48 (2006.01) A61L 27/56 (2006.01) C08H 1/00 (2006.01) C08K 3/26 (2006.01) C08K 3/32 (2006.01) C08K 3/40 (2006.01) D06M 15/15 (2006.01) D06N 3/00 (2006.01) D06N 7/00 (2006.01)

Patent

CA 2372276

Self-supporting, shaped, three-dimensional cross-linked proteinaceous biopolymeric materials that may be implanted in vivo, and methods of making such materials are disclosed. The biopolymeric materials most preferably include reinforcing media, such as biocompatible fibrous or particulate materials. In use, the preformed, shaped biopolymeric materials may be applied to tissue in need of repair and then sealed around its edges with a liquid bioadhesive. In such a manner, repaired tissue which is capable of withstanding physiological pressures may be provided.

La présente invention concerne des matériaux biopolymères protéiniques réticulés en trois dimensions, conformés et autoportants pouvant être implantés in vivo, et des procédés de réalisation de tels matériaux. De manière très préférentielle, les matériaux biopolymères comportent une charge renforçante, tels des matériaux fibreux ou particulaires biocompatibles. En utilisation, les matériaux biopolymères préformés et profilés peuvent être utilisés pour des tissus qui ont besoin d'être réparés et refermés autour des bords avec un liquide bioadhésif. Cela permet au tissu ainsi réparé de résister aux pressions physiologiques.

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