Self-supporting sheet-like material of cross-linked fibrin...

A - Human Necessities – 61 – L

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A61L 31/00 (2006.01) A61K 9/70 (2006.01) A61L 15/32 (2006.01) A61L 27/22 (2006.01) A61L 31/04 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2207992

The self-supporting sheet-like material of cross-linked fibrin has a regular pore size. It is used as a bio-mechanical barrier for the treatment of internal traumatic lesions, in particular for the prevention of adhesion formation as post-operative complication. In the course of this it can be used either alone or in combination with a fibrin glue acting as a haemostatic agent. Since the material in terms of its composition and general structure is similar to endogenous products, it has, inter alia, an excellent bio- compatibility, bio-degradability and bio-resorbability.

Ce matériau du type feuille autonome, composé de fibrine réticulée, présente une grosseur de pores régulière. Il est utilisé comme barrière bio-mécanique pour le traitement de traumatismes internes, en particulier pour prévenir la formation post-opératoire des adhérences. Il peut à cet effet être utilisé seul ou en combinaison avec une colle à base de fibrine agissant comme agent hémostatique. Comme la composition et la structure générale de ce matériau sont semblables à celles des produits endogènes, il présente, entre autres, une biocompatibilité, une biodégradabilité et une aptitude à la biorésorption excellentes.

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