Semaphorin-like proteins and methods of using same

Details Semaphorin-like proteins and methods of using same Semaphorin-like proteins and methods of using same

G - Physics

01

N

G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 5/06 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2487939

The proteins of the invention are a family used to modulate the activity of cells and their ability to attract blood vessels. The proteins are used to inhibit angiogenesis, inhibit cell migration, and inhibit actin filament formation. These proteins are used in this context to diagnose and treat proliferative disorders such as cancer.

Les protéines décrites dans cette invention constituent une famille utilisée pour moduler l'activité de cellules et leur aptitude à attirer les vaisseaux sanguins. Ces protéines sont utilisées pour inhiber l'angiogenèse, la migration cellulaire et la formation de filaments d'actine. Ces protéines servent dans ce contexte à diagnostiquer et à traiter des maladies prolifératives telles que le cancer.

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