Semi-permeable microcapsule with covalently linked layers...

Details Semi-permeable microcapsule with covalently linked layers... Semi-permeable microcapsule with covalently linked layers...

A - Human Necessities

61

K

A61K 35/39 (2006.01) A61J 3/07 (2006.01) A61K 9/50 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2445363

The present invention relates to semi-permeable microcapsules, which exhibit an increased resistance to mechanical stresses as well as an increased resistance to chemical degradation. More specifically, this semi-permeable microcapsule has a bead enclosing a material such as living cells, covalently linked to a semi-permeable layer, made of a polycation cross-linking derivative, covering the bead. The present invention is also directed to a pharmaceutical composition comprising the above-mentioned semi-permeable microcapsules. The present invention is also directed to the use of such microcapsule in a method for microencapsulating a beaded material and in a method for treating diabetes in a subject.

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