Semi-soft c-class immunostimulatory oligonucleotides

Details Semi-soft c-class immunostimulatory oligonucleotides Semi-soft c-class immunostimulatory oligonucleotides

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 31/7088 (2006.01) A61K 31/7125 (2006.01) A61K 39/39 (2006.01) A61P 29/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2578844

The invention relates to specific C-Class semi-soft CpG immunostimulatory oligonucleotides that are useful for stimulating an immune response. In particular the oligonucleotides are useful for treating allergy, such as allergic rhinitis and asthma, cancer and infectious disease, such as hepatitis B and hepatitis C.

L'invention concerne des oligonucléotides immunostimulateurs spécifiques CpG de la classe C à squelette partiellement stabilisé qui permettent de stimuler une réaction immunitaire. Ces oligonucléotides sont utiles en particulier dans le traitement de l'allergie, p. ex. rhinite allergique et asthme, le cancer et les maladies infectieuses telles que l'hépatite B et l'hépatite C.

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