Semi-solid immediate-release oral formulations comprising an...

Details Semi-solid immediate-release oral formulations comprising an... Semi-solid immediate-release oral formulations comprising an...

A - Human Necessities

61

K

A61K 9/48 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2515887

The present invention relates to a pharmaceutical composition suitable for oral administration, in the form of semisolid matrix, comprising an active ingredient poorly soluble in water and present in a quantity of from 15 to 45% by weight of the percent composition of the pharmaceutical composition; a surfactant agent constituted by a polyglycolised glyceride; and a pharmaceutically acceptable hydrophilic carrier.

L'invention concerne une composition pharmaceutique, apte à l'administration par voie orale, se présentant sous forme d'une matrice semi-solide et comprenant un agent actif faiblement soluble dans l'eau et présent en une quantité allant de 15 à 45 % en poids de la composition pharmaceutique. La présente invention porte également sur un agent tensioactif contenant une glycéride polyglycolysée, et sur un excipient hydrophile pharmaceutiquement acceptable.

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