Semi-synthesis of taxane intermediates and aziridine...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 305/14 (2006.01)

Patent

CA 2598707

A process is provided for the semi-synthesis of taxane intermediates and aziridine analogues of cephalomannne and baccatin III intermediates, and the conversion of such intermediates and analogues to paclitaxel and docetaxel.

La présente invention se rapporte à un procédé de semi-synthèse d'intermédiaires de taxane et d'analogues d'aziridine d'intermédiaires de céphalomannine et de baccatine III, et à la transformation de ces intermédiaires et analogues en paclitaxel et en docétaxel.

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