Semi-synthetic route for the preparation of paclitaxel...

Details Semi-synthetic route for the preparation of paclitaxel... Semi-synthetic route for the preparation of paclitaxel...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01)

Patent

CA 2533414

An improvement has been provided in the preparation of docetaxel . This improvement process involves the conversion of 9-dihydro-13-acetylbaccatinIII to docetaxel by the step of removing the docetoxyl protective side chain from 7-O-triethylsilyl- 9,10- diketodocetaxel.

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