Semisynthesis process for the preparation of...

Details Semisynthesis process for the preparation of... Semisynthesis process for the preparation of...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01)

Patent

CA 2582545

The invention relates to a process for the preparation of 10-deacetyl- N~debenzoyl-paclitaxel, a synthon useful for the preparation of taxanes with antitumour activity, and intermediates for the preparation thereof. The invention also discloses a process for the preparation of Docetaxel starting from said compound of formula (I).

L'invention concerne un processus de préparation de 10-déacétyl-N-débenzoyl-paclitaxel, syntone utile dans la préparation de taxanes possédant une activité antitumorale, et des intermédiaires de préparation correspondants. L'invention concerne aussi un processus de préparation de Docetaxel à partir dudit composé ayant la formule (I).

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