Semisynthetic erythromycin antibiotics

Details Semisynthetic erythromycin antibiotics Semisynthetic erythromycin antibiotics

C - Chemistry, Metallurgy

07

H

167/185, 260/230

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1294615

SEMISYNTHETIC ERYTHROMYCIN ANTIBIOTICS William R. Baker Jerry D. Clark Abstract Semisynthetic antibiotics with improved therapeutic properties made from erythromycin are disclosed. 11,12-Cyclic carbamates of erythromycin, its derivatives, and their salts and esters show superior in vitro antimicrobial activity and reduced hepatotoxicity compared to the parent compounds.

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