Sense and antisense peptides to treat multiple sclerosis

Details Sense and antisense peptides to treat multiple sclerosis Sense and antisense peptides to treat multiple sclerosis

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61K 35/76 (2006.01) A61K 38/03 (2006.01) A61K 38/19 (2006.01) C07K 14/47 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2201274

This invention pertains to the novel use of sense and antisense peptides for the treatment of demyelinating disease. A method for identifying epitopes which become exposed in degenerating myelin is described, as well as methods for designing stable peptides to neutralize the immunogenic effect of the epitopes.

L'invention concerne l'utilisation nouvelle de peptides sens et antisens pour traiter une maladie démyélinisante. On décrit également une méthode d'identification des épitopes qui deviennent exposés dans la myéline en dégénératio, ainsi que des méthodes pour concevoir des peptides stables qui neutraliseront l'effet immunogène des épitopes.

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