Sensitization of cells to cytotoxic agents using...

A - Human Necessities – 61 – K

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Details

A61K 45/06 (2006.01) A61K 31/7088 (2006.01) A61K 33/24 (2006.01) A61K 33/40 (2006.01) A61K 41/00 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2405549

This invention relates to the fields of molecular biology and oncology. More particularly, this invention relates to the sensitization of cancerous cells to therapeutic agents. The invention provides methods, compositions, and formulations for potentiating or enchancing the toxicity of various cytotoxins and oxidizing agents, and of reducing the resistance and proliferation rate of cancer cells. It also provides various compositions and therapeutic formulations useful as anticancer agents.

L'invention relève du domaine de la biologie moléculaire et de l'oncologie. Plus spécialement, l'invention concerne la sensibilisation de cellules cancéreuses à des agents thérapeutiques. L'invention concerne des méthodes, des compositions et des formulations destinées à potentialiser ou à augmenter la toxicité de diverses cytotoxines et d'agents oxydants, et à réduire la résistance et le taux de prolifération des cellules cancéreuses. L'invention concerne diverses compositions et formulations thérapeutiques utiles en tant qu'agents anticancéreux.

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