Sensor for detection of carbohydrate

G - Physics – 01 – N

Patent

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G01N 33/543 (2006.01)

Patent

CA 2589547

A sensor for the detection or measurement of carbohydrate analyte (such as glucose) in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal (such as a FRET assay) retained by a material that permits diffusion of analyte but not the assay components, the assay components comprising: an animal lectin; and an analyte analogue capable of competing with analyte for binding to the lectin.

Cette invention a pour objet un capteur de détection ou de mesure d'analyte d'hydrates de carbone (de type glucose) sous forme de fluide comportant des composants d'un dosage par liaison compétitive dont l'affichage est un signal optique détectable ou mesurable (du type dosage FRET) retenu par une substance qui permet la diffusion de l'analyte mais non la diffusion des composants de dosage, les composants de dosage contenant une lectine animale et un analogue d'analyte capable de concurrencer l'analyte pour se lier à la lectine.

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