Sensor for optical assay

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 1/40 (2006.01) C12Q 1/00 (2006.01) G01N 21/77 (2006.01) G01N 27/327 (2006.01) G01N 21/75 (2006.01)

Patent

CA 2137655

Sensor devices for use in assaying for a substance selected from (i) enzymes capable of producing a change in their environment as a result of catalytic reaction with a substrate and (ii) substrates for such enzymes is described, the devices comprising an optical waveguide having immobilised directly or indirectly on a discrete region ("the measurement region") of one longitudinal surface thereof a species whose optical properties change as a result of the aforementioned change in its environment together with the member of an enzyme substrate/enzyme pair complementary to the substance under assay. Methods of assay using such devices are also described.

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