Sensors for electrically sensing binding events for...

Details Sensors for electrically sensing binding events for... Sensors for electrically sensing binding events for...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) G01N 33/559 (2006.01)

Patent

CA 2274245

A first sensor (18) for electrically sensing a molecular binding event includes a receptor-supporting element (20) into which a reagent is diffusable, at feast one molecular receptor (22) supported by the receptor- supporting element (20), and a first electrode (24) embedded in the receptor-supporting element (20). A second sensor for electrically sensing a molecular binding event includes a receptor-supporting element (130), at least one molecular receptor (132) supported by the receptor- supporting element (130), an electrode (134) coupled to the receptor-supporting element (130), and a porous electrode (136) coupled to the receptor-supporting element (130).

Selon cette invention, un premier capteur (18) permettant de détecter électriquement un phénomène de liaison moléculaire comprend un support de récepteur (20) dans lequel un réactif peut se diffuser, au moins un récepteur moléculaire (22) soutenu par le support précité (20), et une première électrode (24) encastrée dans ce même support (20). Un second capteur permettant de détecter électriquement un phénomène de liaison moléculaire comprend un support de récepteur (130), au moins un récepteur moléculaire (132) soutenu par ledit support (130), une électrode (134) couplée au support (130), et enfin, une électrode poreuse (136) couplée au support de récepteur (130).

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