Separation device, analysis system, separation method, and...

B - Operations – Transporting – 01 – D

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B01D 69/00 (2006.01) B01D 57/02 (2006.01) B01D 61/00 (2006.01) B01D 61/18 (2006.01) B01D 61/24 (2006.01) B01D 61/28 (2006.01) B01D 67/00 (2006.01) B01D 69/02 (2006.01) B01D 71/02 (2006.01) B01L 3/00 (2006.01) B81B 1/00 (2006.01) G01N 1/10 (2006.01) G01N 30/88 (2006.01) G01N 37/00 (2006.01) G01N 1/28 (2006.01) G01N 1/38 (2006.01) G01N 30/60 (2006.01)

Patent

CA 2465099

A separating device which comprises two flow route grooves separated by a partition wall and, provided between them, a plurality of separation routes which pass only the molecules having a predetermined size or less; and a separation method using the device. The separation method allows the separation of a substance having a small size, such as a cell, a nucleic acid and a protein to be carried out with a small amount of a sample, in a short time, with excellent resolution, and without causing problems of clogging and the like.

La présente invention concerne un dispositif de séparation qui comprend deux rainures de voie d'écoulement, séparées par une paroi de séparation et présentant entre elles une pluralité de voies de séparation qui laissent passer seulement les molécules qui présentent une taille prédéfinie ou inférieure. La présente invention concerne également un procédé de séparation qui met en oeuvre ledit dispositif et qui permet de séparer rapidement une substance de petite taille, telle qu'une cellule, un acide nucléique et une protéine, avec une petite quantité d'échantillon, avec une très bonne résolution et sans causer de problèmes d'engorgement ou similaires.

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