Separation matrix and method of purification

Details Separation matrix and method of purification Separation matrix and method of purification

C - Chemistry, Metallurgy

08

F

C08F 251/00 (2006.01)

Patent

CA 2570624

The present invention relates to a separation matrix comprised of a porous support to which ligands have been immobilised, wherein said ligands comprise at least one sulphonamide and the R group of the sulphonyl comprises an aromatic group. The nitrogen of the sulphonamide may be a secondary or tertiary amine. The invention also relates to a chromatography column that contains the described separation matrix, as well as to a method of isolating immunoglobulin-like compounds by adsorption to the separation matrix.

L'invention se rapporte à une matrice de séparation composée d'un support poreux sur lequel sont fixés de ligands. Ces ligands comprennent au moins un sulfonamide, et le groupe R du sulfonyle comprend un groupe aromatique. L'azote du sulfonamide peut être une amine secondaire ou tertiaire. L'invention concerne également une colonne de chromatographie qui contient la matrice de séparation décrite, ainsi qu'un procédé permettant d'isoler des composés de type immunoglobulines par adsorption sur la matrice de séparation.

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