Separation method of .alpha.-l-aspartyl-l-phenylalanine...

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5.06, 530/1.

C07K 5/075 (2006.01) C07K 1/30 (2006.01) C07K 5/072 (2006.01)

Patent

CA 1339657

A method for separating .alpha.-L-aspartyl-L- phenylalanine methyl ester (.alpha.-APM) from a solution containing .alpha.-APM and impurities associated with the production thereof which comprises adding a mineral acid or an organic sulfonic acid to the solution in an organic carboxylic acid or in a solvent containing an organic carboxylic acid, and isolating the pure salt of .alpha.-APM which precipitates therefrom.

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