Separation of hemoglobin on hydroxyapatite using hplc

Details Separation of hemoglobin on hydroxyapatite using hplc Separation of hemoglobin on hydroxyapatite using hplc

C - Chemistry, Metallurgy

07

K

C07K 14/805 (2006.01) A61K 38/42 (2006.01) C07K 1/16 (2006.01)

Patent

CA 2222755

A method for producing a stable polymerized hemoglobin blood-substitute from blood. The method of this invention includes contacting a polymerized hemoglobin solution with a hydroxyapatite HPLC column and recovering with substantially pure polymerized hemoglobin.

Cette invention se rapporte à un procédé pour produire à partir du sang un succédané du sang qui est de l'hémoglobine polymérisée et stable. Ce procédé consiste à mettre une solution d'hémoglobine polymérisée en contact avec une colonne de chromatographie liquide à haute performance sur hydroxyapatite et à récupérer l'hémoglobine polymérisée pratiquement pure.

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