Separation of isomers of furo (3,4-c) pyridine derivatives

Details Separation of isomers of furo (3,4-c) pyridine derivatives Separation of isomers of furo (3,4-c) pyridine derivatives

C - Chemistry, Metallurgy

07

D

260/276.2

C07D 491/048 (2006.01) C07D 491/04 (2006.01) C07H 17/00 (2006.01)

Patent

CA 2013649

This invention relates to a method for the separation of stereoisomers of 7-hydroxy-furo[3,4-c]pyridine derivatives of the formula Image wherein R3, R4 and R6 represent various substituents, which comprises reacting a fully O-acetylated monosaccharide halogenide with a racemate of the selected 7-hydroxy-furo[3,4-c]pyridine derivative, to form the (+) and (-) (O-acetylated monosaccharide) (furo[3,4-c] pyridine 7-yl derivative) ethers, then separating the (+) and the (-) ethers by selective crystallization, in an hydroalcoholic medium, either of the acetylated forms or of the corresponding desacetylated forms and, finally, working up each of the separated derivatives by the usual routes.

Affiliated with

Also associated with

Rating

Separation of isomers of furo (3,4-c) pyridine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Separation of isomers of furo (3,4-c) pyridine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Separation of isomers of furo (3,4-c) pyridine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1817097