Separation of plasma or serum from whole blood using a red...

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/14 (2006.01) B01D 24/02 (2006.01) B01D 39/14 (2006.01) B01L 3/00 (2006.01) G01N 1/34 (2006.01) G01N 33/48 (2006.01) G01N 33/49 (2006.01) G01N 33/50 (2006.01) G01N 33/66 (2006.01) G01N 33/80 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2104976

ABSTRACT OF THE DISCLOSURE The present invention relates to a reagent for forming stabilized, clumped red blood cells, comprising a red blood cell binding component and a polycationic polymer component. The invention further relates to a method for separating plasma or serum from whole blood, comprising contacting whole blood with a red blood cell binding component and a polycationic polymer component to form stabilized, clumped red blood cells and then removing the stabilized, clumped red blood cells from the plasma or serum. The invention also relates to a device for separating plasma or serum from whole blood, comprising a clumping layer, which comprises a red blood cell binding component and a polycationic polymer component, a hematocrit reducing layer and a free cell removing layer and a method for using such a device, comprising introducing whole blood into the device and causing the whole blood to pass through the device.

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