Separation of the enantiomers of piperidone derivatives with...

Details Separation of the enantiomers of piperidone derivatives with... Separation of the enantiomers of piperidone derivatives with...

C - Chemistry, Metallurgy

07

D

C07D 211/74 (2006.01) C07B 57/00 (2006.01)

Patent

CA 2409614

The invention relates to a process which can be used on an industrial scale for dynamically separating the enantiomers of piperidone derivatives of general formula (1) (see formula 1) wherein R1, R2, R3 and n may have the meanings given in the specification and claims, with simultaneous in situ racemisation of the unreacted enantiomer.

La présente invention concerne un procédé pouvant être mise en oeuvre à l'échelle de la technique servant à séparer de manière dynamique des énantiomères de dérivés de pipéridone de formule générale (1) dans laquelle R<1>, R<2>, R<3> et n correspondent aux éléments indiqués dans la description et dans les revendications, en même temps que s'effectue une racémisation in situ de l'énantiomère non converti.

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