Separation process and dyes for use therewith

Details Separation process and dyes for use therewith Separation process and dyes for use therewith

C - Chemistry, Metallurgy

07

D

C07D 311/82 (2006.01) C07D 311/80 (2006.01) C07K 1/107 (2006.01) C07K 1/26 (2006.01)

Patent

CA 2486224

The present invention describes rhodamine compounds particularly well-suited for pre-labeling a protein that is then subjected to two-dimensional electrophoresis. Isomeric purification and synthesis of a dye having net neutral charge or no charge precludes interference with isoelectric electrophoretic separation.

La présente invention concerne des composés de rhodamine particulièrement adaptés au pré-marquage d'une protéine qui est alors soumise à une électrophorèse bidimensionnelle. La purification isomérique et la synthèse d'un colorant ayant une charge neutre ou aucune charge empêche les interférences avec la séparation électrophorétique isoélectrique.

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