Separation process and products obtained thereby

C - Chemistry – Metallurgy – 11 – B

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182/15.4

C11B 7/00 (2006.01) A23J 7/00 (2006.01) C11B 3/00 (2006.01)

Patent

CA 1179278

ABSTRACT OF THE DISCLOSURE The invention provides a process for fractionation of compounds, which in essentially non-polar solvents form mixed or co-micelles, and hence cannot normally be fractionated by membrane filtration. By dissolving a mixture of such compounds in a solvent system in which selective micelles formation occurs, and contacting the solution under pressure with a semipermeable membrane to separate the mixture into a permeate and a retentate, fractionation of the compound mixture can be achieved, i.e. a fraction enriched in one of said compounds can be recovered from the permeate and/or retentate by re- oving solvent therefrom. The new process is in partic- ular useful for fractionating phosphatides-containing mixtures into a fraction enriched in phosphatidyl choline by ultrafiltration of a solution of the mixture in a solvent system comprising an essentially non-polar solvent and a polar solvent. e.g. hexane-ethanol, etc. through a semipermeable membrane, and recovering a frac- tion enriched in phosphatidyl choline from the permeate. A fraction enriched in phosphatidyl inositol can be re- covered from the retentate.

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