Sequence determination of nucleic acids using electronic...

Details Sequence determination of nucleic acids using electronic... Sequence determination of nucleic acids using electronic...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C40B 70/00 (2006.01)

Patent

CA 2380258

The present invention is directed to methods and compositions for the use of self-assembled monolayers to electronically detect nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs).

La présente invention concerne des procédés et des compositions faisant intervenir des monocouches auto-assemblées pour la détection électronique d'acides nucléiques, en particulier d'altérations telles que des substitutions nucléotidiques (mésappariement) et des polymorphismes nucléotidiques uniques (SNP).

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