"sequence-specific non-photoactivated crosslinking agents...

Details "sequence-specific non-photoactivated crosslinking agents... "sequence-specific non-photoactivated crosslinking agents...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 17/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2083719

2083719 9118997 PCTABS00008 Agents which bind to the major groove of nucleic acid duplexes in a sequence-specific manner and are capable of forming covalent bonds with one or both strands of the duplex in the absence of light are useful therapeutic agents in the treatment of conditions mediated by duplex DNA. These agents are designed so that the reactivity of the crosslinking agent does not interfere with the sequence specificity of the agent which binds to the major groove. Thus, specific desired DNA duplexes can be targeted and their activity diminished or enhanced.

Affiliated with

Also associated with

Rating

"sequence-specific non-photoactivated crosslinking agents... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with "sequence-specific non-photoactivated crosslinking agents..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and "sequence-specific non-photoactivated crosslinking agents... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1587791