Sequences involved in phenomena of tumour suppression,...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 25/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2438219

The invention concerns in particular novel sequences involved in the molecular pathways of tumour suppression, tumour reversion, apoptosis and/or virus resistance. The invention also concerns the use of said sequences for treatment against cancers, viral diseases, neurodegenerative diseases and in the field of diagnosis and for implementing screening methods for assay of compounds. The invention further concerns methods for detection and/or assay of sequences of the invention or their expression products in a biological sample.

La pr~sente invention concerne notamment de nouvelles s~quences impliqu~es dans les voies mol~culaires de la suppression tumorale, la r~version tumorale, l'apoptose et/ou la r~sistance aux virus. Elle concerne ~galement l'utilisation de ces s~quences ou le traitement contre le cancer, maladies virales, maladies neurod~g~n~ratives ainsi qu'en mati­re de diagnostique ainsi que pour la mise en oeuvre de proc~d~s de criblage de compos~s ~ tester. Cette invention a ~galement pour objet des proc~d~s de d~tection et/ou de dosage des s~quences de l'invention ou de leurs produits d'expression dans un pr~l­vement biologique.

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