Sequencing near infrared and infrared fluorescence labeled...

C - Chemistry – Metallurgy – 09 – B

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C09B 23/12 (2006.01) C07D 209/12 (2006.01) C07D 209/62 (2006.01) C09B 23/01 (2006.01) C12Q 1/68 (2006.01) G01N 21/64 (2006.01) G01N 27/447 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2180894

To sequence DNA automatically, DNA marked with far infrared, near infrared, or infrared fluorescent dyes are electrophoresed in a plurality of channels through a gel electrophoresis slab or capillary tubes wherein the DNA samples are resolved in accordance with the size of DNA fragments in the gel electrophoresis slab or capillary tubes into fluorescently marked DNA bands. The separated samples are scanned photoelectrically with a laser diode and a sensor, wherein the laser scans with scanning light at a wavelength within the absorbance spectrum of said fluorescently marked DNA samples and light is sensed at the emission wavelength of the marked DNA.

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