C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/7.1
C07K 1/08 (2006.01) C07K 7/10 (1990.01)
Patent
CA 1292840
Abstract of the Disclosure A peptide is sequenced from its carboxyl terminal by coupling with an isothiocyanate having a chemical formula R(X)Si(SCN)y where x=0-3 and y=1-4. R may be an alkyl or an aryl. The coupling reaction is preferably conducted at a temperature range of 50°C-90°C for a period to approximately sixty (60) minutes or less. A weak acid anhydride, preferably a carboxylic acid anhydride, or a weak acid chloride, preferably a carboxylic acid chloride, may be mixed with the isothiocyanate. An organic base catalyst selected from a group consisting of tertiary amines including aromatic amines such as pyridine may be utilized.
519119
Beckman Research Institute Of The City Of Hope
Sim & Mcburney
LandOfFree
Sequencing of peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sequencing of peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sequencing of peptides will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1302882