C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
167/129, 530/13,
C07K 7/04 (2006.01) A61K 39/015 (2006.01) C07K 14/445 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 1335320
Synthetic polypeptides constituted by at least two consecutive repeating units of (Asn-Asn-Pro) sequence are powerful immunogens in test animals. The formed antibodies recognize both the synthetic polypeptides and the immuno-dominant epitope of the circumsporozoitic protein of Plasmodium falciparum. Said polypeptides, which can be obtained in pure form, are particularly useful for the preparation of antimalarial vaccines and of diagnostic kits for the determination of malarial affections.
573719
Bonelli Fabio
Pessi Antonello
Verdini Antonio Silvio
Eniricerche S.p.a.
Robic
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