Sequential therapy comprising a 20(s)-camptothecin compound...

Details Sequential therapy comprising a 20(s)-camptothecin compound... Sequential therapy comprising a 20(s)-camptothecin compound...

A - Human Necessities

61

K

A61K 31/545 (2006.01) A61K 31/47 (2006.01) A61K 31/4745 (2006.01) A61K 31/513 (2006.01) A61K 31/7072 (2006.01)

Patent

CA 2476664

A method is provided for treating a patient having a disease associated with undesirable or uncontrolled cell proliferation, the method comprising: administering to the patient a 20(S)-camptothecin compound for a period of time during which a pyrimidine base analog is not being administered to the patient; and administering a pyrimidine base analog to the patient.

L'invention concerne un procédé destiné au traitement d'un patient atteint d'une maladie associée à une prolifération cellulaire indésirable ou incontrôlée. Ce procédé consiste à administrer au patient un composé 20(S)-camptothécine pendant une période durant laquelle un analogue de base pyrimidine n'est pas administré au patient et à administrer un analogue de base pyrimidine au patient.

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