Serine protease inhibitors

Details Serine protease inhibitors Serine protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 311/51 (2006.01) A61K 31/18 (2006.01) C07C 257/16 (2006.01) C07C 257/18 (2006.01) C07C 311/05 (2006.01) C07C 311/06 (2006.01) C07C 311/08 (2006.01) C07C 311/13 (2006.01) C07C 311/18 (2006.01) C07C 311/21 (2006.01) C07C 311/29 (2006.01)

Patent

CA 2356934

Compounds having structure (A) are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.

L'invention concerne des composés présentant la structure représentée ci-dessous utiles pour l'inhibition d'enzymes sérine protéases, tels que le TF/facteur VIIa, le facteur Xa, la thrombine et la kallikréine. Ces composés peuvent convenir pour des méthodes de prévention et/ou de traitement de troubles de la coagulation.

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