Serine protease inhibitors

Details Serine protease inhibitors Serine protease inhibitors

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07D 401/12 (2006.01) C07D 417/14 (2006.01) C07K 5/02 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/072 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2246722

The invention relates to a compound having formula (I), wherein A, B, X, Y and r are as defined in the description, or a prodrug thereof or a pharmaceutically acceptable salt thereof. The compounds of the invention have anticoagulant activity and can be used in treating or preventing thrombin- related diseases.

L'invention concerne un composé de la formule (I). Dans cette formule, A, B, X, Y et r sont comme définis dans la description. L'invention concerne également un précurseur de ce composé ou un sel de celui-ci acceptable sur le plan pharmaceutique. Le composé de l'invention a une activité d'anticoagulant et il peut être utilisé pour traiter ou prévenir des maladies associées à la thrombine.

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