Serine protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/18 (2006.01) A61K 31/496 (2006.01) A61P 29/00 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 211/26 (2006.01) C07D 211/46 (2006.01) C07D 211/58 (2006.01) C07D 213/36 (2006.01) C07D 213/38 (2006.01) C07D 213/56 (2006.01) C07D 295/185 (2006.01) C07D 309/32 (2006.01) C07D 309/34 (2006.01) C07D 335/02 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2411805

Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.

La présente invention concerne des composés représentés par la formule (I) dans laquelle R¿2?, X, Y, Cy, L and Lp(D)¿n? sont tels que décrits dans le descriptif. Ces composés sont des inhibiteurs de la sérine protéase, en particulier le Facteur Xa, utilisés dans le traitement des maladies cardio-vasculaires.

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