Serine proteinase inhibitory activity by hydrophobic...

Details Serine proteinase inhibitory activity by hydrophobic... Serine proteinase inhibitory activity by hydrophobic...

A - Human Necessities

61

K

A61K 31/65 (2006.01) A61K 8/35 (2006.01)

Patent

CA 2283071

A method for inhibiting the activity of serine proteinase in biological systems includes administering to the system a serine proteinase inhibitory amount of a hydrophobic 4-de(dimethylamino) tetracycline. The method reduces tissue destruction during inflammation resulting from the activity of human leukocyte elastase. The method is used for pharmaceutical and cosmetic purposes.

Procédé permettant d'inhiber l'activité de la sérine protéinase dans des systèmes biologiques. Ce procédé consiste à apporter au système une quantité de 4-de(diméthylamino)tétracycline hydrophobe inhibitrice de la sérine protéinase. Le procédé réduit la destruction des tissus au cours de l'inflammation résultant de l'activité de l'élastase leucocytaire humaine. Le procédé est utilisé à des fins pharmaceutiques et cosmétiques.

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