Serological test for gonorrheal antibodies

Details Serological test for gonorrheal antibodies Serological test for gonorrheal antibodies

G - Physics

01

N

167/44

G01N 31/02 (2006.01) A61K 39/095 (2006.01) G01N 33/571 (2006.01)

Patent

CA 1045031

ABSTRACT Disclosed is a reagent used for serological detection of gonorrheal antibodies in human blood serum or synovial fluid. The reagent comprises latex particles having absorbed on their surfaces an inert protein, such as bovine serum albumin, and a heat labile antigen derived from Neisseria gonorrhoeae bacteria exhibiting T1 colonial morphology. The reagent may be employed in several forms, for example, as a liquid suspension of the latex particles, or in the form of a dried deposit of the latex particles. Regard- less of the form employed, the reagent is particularly useful as a routine screening test in hospitals and prenatal clinics to detect gonococcal infect- ion in women and also in cases of complicated gonorrhea, e.g., gonorrheal arthritis where infection is not conveniently detectable by present means. If desired, diagnosis made by the test of the invention can be subsequently con- firmed by conventional more expensive and time consuming means, if this is thought to be desirable.

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