C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/06 (2006.01) A61K 38/48 (2006.01) A61K 45/00 (2006.01) A61P 29/00 (2006.01) C07H 21/00 (2006.01) C07K 14/81 (2006.01) C12N 9/64 (2006.01) C12N 15/10 (2006.01) C12N 15/12 (2006.01) C12N 15/57 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2678436
Methods, oligonucleotides arrays etc. for treating inflammatory conditions and of predicting subject outcome based on polymorphisms in SERPINE1 and/or PROC, alone or in combination, wherein the method of treatment includes administering to the subject an anti- inflammatory agent or an anti-coagulant agent, wherein said subject is determined to have an improved response genotype or combination.
L'invention porte sur des procédés, des réseaux d'oligonucléotides, etc.qui permettent de traiter des états inflammatoires et de prédire l'évolution d'un sujet sur la base des polymorphismes de la SERPINE1 et/ou de PROC, seuls ou combinés, le procédé de traitement consistant à administrer au sujet un agent anti-inflammatoire ou un agent anticoagulant, ledit sujet ayant été reconnu comme présentant un génotype ou une combinaison de génotypes de réponse améliorée.
Close Kirkwood Sandra
Gordon Anthony
Macias William Louis
Russell James A.
Siddiqui Asim Sarosh
Sirius Genomics Inc.
Smart & Biggar
The University Of British Columbia
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