Sers-based, single step, real-time detection of protein...

Details Sers-based, single step, real-time detection of protein... Sers-based, single step, real-time detection of protein...

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01) B82Y 30/00 (2011.01) C12M 1/42 (2006.01) C12Q 1/42 (2006.01) C23C 4/04 (2006.01) C23C 4/12 (2006.01) C40B 30/08 (2006.01) C40B 50/14 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2709456

This invention provides novel compositions and methods for the detection, and/or quantification, of the presence and/or activity of one or more kinases and/or phosphatases. In certain embodiments this invention a device for the detection of kinase and/or phosphatase activity where the device comprises a Raman active surface comprising features that enhance Raman scattering having attached thereto a plurality of kinase and/or phosphatase substrate molecules.

L'invention concerne de nouvelles compositions et des procédés pour la détection et/ou la quantification de la présence et/ou l'activité d'une ou de plusieurs kinases et/ou phosphatases. Dans certains modes de réalisation, cette invention porte sur un dispositif permettant la détection de l'activité kinase et/ou phosphatase, le dispositif comprenant une surface active de Raman comprenant des caractéristiques qui augmentent la diffusion Raman à laquelle sont attachées plusieurs molécules de substrat de kinase et/ou de phosphatase.

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