Sertraline polymorph

Details Sertraline polymorph Sertraline polymorph

C - Chemistry, Metallurgy

07

C

C07C 211/42 (2006.01)

Patent

CA 2224387

A novel polymorph of sertraline hydrochloride, i.e. (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride, is disclosed, having improved water solubility along with acceptable stability. It is characterized by a unique x-ray diffraction pattern and unit cell structure, as well as IR and NMR spectral characteristics.

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