Serum biomarkers for chagas disease

G - Physics – 01 – N

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Details

G01N 33/68 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) G01N 27/00 (2006.01) G01N 30/96 (2006.01) G01N 33/53 (2006.01) H01J 49/04 (2006.01)

Patent

CA 2547861

The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Chagas disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with Chagas disease or non-infected. The biomarkers can be detected by SELDI mass spectrometry.

La présente invention concerne des biomarqueurs protéiques et des combinaisons de biomarqueurs utilisés dans la qualification du stade de la maladie de Chagas chez un patient. Le biomarqueurs de l'invention sont utilisés, en particulier, dans la classification d'un échantillon d'un sujet infecté par la maladie de Chagas ou non infecté. Les biomarqueurs peuvent être détectés par spectrométrie de masse SELDI.

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