Serum protein-associated target-specific ligands and...

Details Serum protein-associated target-specific ligands and... Serum protein-associated target-specific ligands and...

C - Chemistry, Metallurgy

07

K

C07K 2/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C40B 30/04 (2006.01) G01N 33/53 (2006.01) C07K 14/705 (2006.01) C07K 14/765 (2006.01)

Patent

CA 2490009

Disclosed is an artificial target-specific ligand that binds to both serum albumin and a particular molecular target. Interaction with serum albumin improves properties when administered to a subject. For example, an interaction between the ligand and serum albumin can extend the half-life of the ligand in circulation.

L'invention porte sur un ligand artificiel propre à une cible qui se lie à l'albumine-sérum et à une cible moléculaire particulière. L'interaction avec l'albumine-sérum améliore certaines propriétés lors de l'administration à un sujet. Par exemple, une interaction entre le ligand et l'albumine-sérum peut prolonger la demi-vie du ligand utilisé.

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