Severe sepsis preventive therapeutic agent

A - Human Necessities – 61 – K

Patent

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A61K 31/215 (2006.01) A61K 31/00 (2006.01) A61K 31/223 (2006.01) A61K 31/245 (2006.01) A61K 31/27 (2006.01) A61K 31/277 (2006.01) A61K 31/41 (2006.01) A61K 31/4192 (2006.01) A61K 31/4196 (2006.01) A61K 31/428 (2006.01) A61K 45/00 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 1/06 (2006.01) A61P 1/16 (2006.01) A61P 3/02 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 3/14 (2006.01) A61P 7/02 (2006.01) A61P 7/06 (2006.01) A61P 9/02 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/14 (2

Patent

CA 2481767

The present invention provides an agent for the prophylaxis or treatment of severe sepsis, which contains a compound represented by the formula (I): (see formula I) or, the formula (II): (see formula II) , or a salt thereof or a prodrug thereof, a TLR signal inhibitor containing a non-peptide compound and an agent for the prophylaxis or treatment of organ dysfunction and the like, which contains a TLR signal inhibitory substance.

L'invention concerne un agent thérapeutique pour la prévention d'état septique grave, qui renferme un composé représenté par la formule générale (I) ou (II), y compris un sel ou un promédicament correspondant. L'invention concerne également un inhibiteur de signal de récepteur Toll (TLR) qui renferme un composé non peptidique et un agent thérapeutique pour la prévention de dérèglement d'organe, entre autres, qui renferme un matériau inhibiteur de signal de récepteur TLR.

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