A - Human Necessities – 01 – K
Patent
A - Human Necessities
01
K
A01K 67/02 (2006.01) A01D 19/00 (2006.01)
Patent
CA 2751596
The present invention relates generally to the field of sex determination of animals. Provided are methods and agents to manipulate sex determination, particularly in avian animals such as chickens, through a male chromosome-linked testis (sex) regulatory gene. Expression or activity of the DMRT1 gene or protein is modulated to produce animals with displaying a phenotype sex that differs from their genotype.
La présente invention concerne de manière générale le domaine de la détermination du sexe d'animaux. Elle concerne des procédés et des agents permettant de manipuler la détermination du sexe, en particulier chez les animaux aviaires comme les poulets, au moyen d'un gène régulateur des testicules (sex) lié au chromosome mâle. L'expression ou l'activité du gène ou de la protéine DMRT1 est modulée pour produire des animaux qui présentent un phénotype sexuel qui diffère de leur génotype.
Doran Timothy James
Lowenthal John William
Moore Robert John
Sinclair Andrew
Smith Craig
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Murdoch Childrens Research Institute
The University Of Melbourne
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