C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) C12N 5/076 (2010.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01) C12N 15/09 (2006.01) C12N 15/65 (2006.01) C12N 15/85 (2006.01) C12Q 1/04 (2006.01) C12Q 1/24 (2006.01)
Patent
CA 2442019
The present invention relates to methods and materials for pre-selecting the sex of mammalian offspring. In particular, the materials and methods described herein permit the enrichment of X- or Y-chromosome-bearing sperm in semen by introducing a transgene into a sex chromosome under control of regulatory sequences that provide for expression of the transgene in a haploid-specific manner.
La présente invention concerne des techniques et des matériaux destinées à présélectionner le sexe de la progéniture de mammifères. Ces techniques et ces matériaux permettent en particulier d'enrichir le sperme porteur du chromosome X ou Y dans la semence par introduction d'un transgène dans un chromosome sexuel sous la commande de régions régulatrices qui fournissent l'expression de ce transgène d'une manière spécifiquement haploïde.
Bishop Michael D.
Eilertsen Kenneth J.
Forsberg Erik J.
Leno Gregory H.
Zheng Ying
Gowling Lafleur Henderson Llp
Infigen Inc.
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