A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 31/195 (2006.01) A61K 31/506 (2006.01) A61K 31/53 (2006.01) A61K 31/5377 (2006.01) A61K 45/06 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2749730
The present invention relates to soluble guanylate cyclase (sGC) and to phosphodiesterases (PDEs) and the phar-macology of sGC stimulators, sGC activators and PDE inhibitors. More particularly, the invention relates to the use of sGC stimu-lators and sGC activators in combination with PDE5 inhibitors for preparation of medicaments for the treatment of male erectile dysfunction (MED) in particular for the MED treatment of difficult to treat patients and patients not or not fully responding to PDE5 inhibitors.
La présente invention concerne la cyclase guanylate soluble (sGC) et des phosphodiestérases (PDE), ainsi que la pharmacologie des stimulateurs sGC, des activateurs sGC et des inhibiteurs PDE. Plus particulièrement, l'invention concerne l'utilisation de stimulateurs sGC et d'activateurs sGC en combinaison avec des inhibiteurs PDE5, dans la préparation de médicaments destinés au traitement du dysfonctionnement érectile masculin (MED), et en particulier au traitement du MED pour des patients difficiles à traiter et des patients ne réagissant pas, ou pas totalement, aux inhibiteurs de PDE5.
Boettcher Michael-Friedrich
Sandner Peter
Stasch Johannes-Peter
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
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