A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01)
Patent
CA 2665943
The present invention relates to compositions and methods for blocking entry of Shigella into a cell of an animal, to therefore providing protection against, or reduce the severity of Shigella infections. More particularly it relates to the use of the IpaD protein obtained from natural sources and/or through synthesis or recombinant technology, and conjugates thereof to induce neutralizing antibodies having protective activity against several serotypes of Shigella, in particular S. flexneri. The composition of the invention is useful to prevent and/or treat shigellosis caused by a bacterium of the Shigella family.
La présente invention concerne des compositions et des procédés permettant de bloquer l'entrée de Shigella dans une cellule animale et d'offrir par conséquent une protection contre les infections à Shigella, ou d'en diminuer la gravité. L'invention concerne plus particulièrement l'utilisation de la protéine IpaD, obtenue de sources naturelles et/ou par synthèse ou technologie recombinante, ainsi que des conjugués de cette protéine, pour induire des anticorps neutralisants présentant une activité protectrice contre plusieurs sérotypes de Shigella, en particulier S. flexneri. La composition de l'invention se révèle utile pour prévenir et/ou traiter une shigellose causée par une bactérie du genre Shigella.
Allaoui Abdelmounaaim
Boekema Egbert J.
Botteaux Anne
Parsot Claude
Sani Musa
Inserm (institut National de La Sante Et de La Recherche Medical
Institut Pasteur
Rijksuniversiteit Groningen
Robic
Universite Libre de Bruxelles
LandOfFree
Shigella ipad protein and its use as a vaccine against... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Shigella ipad protein and its use as a vaccine against..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Shigella ipad protein and its use as a vaccine against... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2007780