Ship 1 modulator prodrugs

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 219/28 (2006.01) A61K 31/222 (2006.01) A61K 31/417 (2006.01) A61K 31/661 (2006.01) C07C 235/74 (2006.01) C07C 237/12 (2006.01) C07C 279/14 (2006.01) C07C 323/52 (2006.01) C07D 233/64 (2006.01) C07F 9/12 (2006.01)

Patent

CA 2656339

The present invention provides the use of prodrugs of pelorol and homopelorol, related compounds and pharmaceutical compositions thereof as modulators of SHIPl activity. A compound or a pharmaceutical composition of the present invention may be used for the treatment or prophylaxis of an inflammatory, neoplastic, hematopoetic or immune disorder or condition in addition to other disorders and conditions.

L'invention concerne l'utilisation de promédicaments de pélorol et d'homopélorol, des composés apparentés et des compositions pharmaceutiques à base de ceux-ci comme modulateurs de l'activité SHIPl. On peut utiliser un composé ou une composition pharmaceutique de la présente invention pour le traitement ou la prophylaxie d'un trouble ou d'un état inflammatoire, néoplasique, hématopoïétique ou du système immunitaire en plus d'autres troubles et états.

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