Short acting benzothiazepine calcium channel blockers and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/554 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2734780

The present invention relates to short-acting calcium channel blocking compounds and their use to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension in general, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods.

La présente invention concerne des composés bloqueurs de canal calcique à action courte et leur utilisation pour traiter des cardiopathies ischémiques, des arythmies cardiaques, une crise d'hypertension dans le cadre d'un service d'urgences, une hypertension préalable, concomitante ou faisant suite à une intervention chirurgicale, un phénomène de non reperfusion faisant suite à une reperfusion, et des maladies associées à une diminution de l'irrigation sanguine des muscles squelettiques. L'invention concerne également des compositions pharmaceutiques formulées en vue de leur utilisation dans le cadre des procédés, et des kits pour de tels procédés.

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