Short-acting, ester-containing .beta.-adrenergic blocking...

C - Chemistry – Metallurgy – 07 – D

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260/477.6, 260/4

C07D 309/12 (2006.01) C07D 213/30 (2006.01)

Patent

CA 1180344

Abstract of the Disclosure A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: Image wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.

390967

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